About cesium carbonate

cesium carbonate is a white crystalline solid compound. Caesium carbonate has a high solubility in polar solvents such as water, alcohol and DMF. Its solubility is higher in organic solvents compared to other carbonates like potassium and sodium carbonates, although it remains quite insoluble in other organic solvents such as toluene, p-xylene, and chlorobenzene. This compound is used in organic synthesis as a base. It also appears to have applications in energy conversion.
Caesium carbonate is very important for the N-alkylation compounds such as sulfonamides, amines, β-lactams, indoles, heterocyclic compounds, N-substituted aromatic imides, phthalimides, and several similar other compounds. Research on these compounds has focused on their synthesis and biological activity. In the presence of gold sodium chloride (NaAuCl4), caesium carbonate is very efficient mechanism for aerobic oxidation of different kinds of alcohols into ketones and aldehydes at room temperature without additional polymeric compounds. There is no acid formation produced when primary alcohols are used. The process of selective oxidation of alcohols to carbonyls had been quite difficult due to the nucleophilic character of the carbonyl intermediate. In the past Cr(VI) and Mn(VII) reagents have been used to oxidize alcohols, however, these reagents are thought to be toxic to the environment, and are pricy. Caesium carbonate can also be used in Suzuki, Heck, and Sonogashira synthesis reactions. Caesium carbonate produces carbonylation of alcohols and carbamination of amines more efficiently than some of the mechanisms that have been introduced in the past. Caesium carbonate can be used for sensitive synthesis when a balanced strong base is needed.