Combretastatin Information

Combretastatin is a small organic molecule found in the bark of the African bush willow tree Combretum caffrum (photo, right), identified 21 years ago by Professor George R. Pettit, the Director of the Cancer Research Institute based at Arizona State University in the USA. (See Pettit et al. Can. J. Chem. 610 (1982), 1374). Scientists at the CRI have not only completed a total synthesis for combretastatin, but have isolated it on scales large enough to allow clinical testing, and they have also produced water-soluble phosphate derivatives, which are helping the drug's delivery to patients. Professor Pettit, like many great scientists, is driven towards a goal, that of finding treatments for cancers. He has many lead compounds and is a well-known scientist in the world of Natural Products Chemistry. I had the pleasure of working with the legendary "medicine man" from 1992-1994.
The beautiful Bush Willow tree only grows on the banks of rivers in the Eastern Cape Province of South Africa. Local historians believe that for over 2000 years Arabians traded for the bark with the San people (Bushmen). The bark was probably used as a general tonic in those days, because, apart from its anti-cancer properties, the bark also produces a feeling of improved general well being. Like many useful natural extracts it can be harmful in the wrong dose. This can be clearly illustrated by the fact that it has been used as a poison for Zulu spears. It is now possible to order the bark online at a cost of $22/100g Only take medicines, of any kind, in consultation with a trained, accredited medical practitioner.
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What is Corilagin

Corilagin is a gallotannin. It can be found in Alchornea glandulosa.

References

1,New TNF- Releasing Inhibitors, Geraniin and Corilagin, in Leaves of Acer nikoense, Megusurino-ki

  Biological & Pharmaceutical Bulletin  Vol. 24 (2001) , No. 10 1145

2,Antiatherogenic Effects of Phyllanthus Emblica Associated with Corilagin and its Analogue

   YAKUGAKU ZASSHI Vol. 125 (2005) , No. 7 587-591

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Description of Fungal Amylase

Product name  : Fungal Amylase
Applications : Baking industry,Increasing yield of beer and alcohol breweries by supplement with malts,Feed additives,High maltose syrup (D.E. 40 to 45) manufacturing.
Description : Deerland Fungal Amylase Concentrate is an enzyme preparation derived from Aspergillus oryzae and contains high alpha-Amylase activity that converts solubilized or liquefied starch to mainly maltose.
Request Info : 
Supplier : Deerland Enzymes
Contact info  : 3800 Cobb International Blvd. Kennesaw. GA 30152, United States
Phone:800-697-8179 
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The role of the aconitine

Aconitine Aconitum, Aconitum, monkshood plant, the main toxic components. Oral pure aconitine 0.2mg can be poisoned, 3-5mg can be lethal. The common folk Aconitum, Aconitum plants to cook the wine. This product has analgesic effects, clinically used to relieve pain, especially for digestive system cancer pain; topical when the paralysis of the peripheral nerve endings, produce a local anesthetic and analgesic effects; anti-inflammatory effect, This product is highly toxic, can excited paralysis of sensory nerves and central nervous, excited, paralysis of cholinergic nerves and respiratory center, excited cardiac vagal directly toxic to myocardial cells. There are sweating.
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The nature of the catechin (C)

Catechin (C) is a white to brown crystalline powder, discoloration in the air. Density 1.54g/cm3. The melting point of about 200 ° C (decomposition). Dissolved in 50 parts of water; soluble in alcohol, ether. Leaves, Ilex plant holly (Ilex chi-nensis Sims) of leaves and other plants exist in the scales beginning of fern plants black fern Stenoloma chusanum (L.) Ching]. Catechin (C) has an antibacterial effect in vitro tests have varying degrees of inhibitory effect of Pseudomonas aeruginosa, Escherichia coli, Salmonella typhi, Shigella, Alcaligenes and Bacillus subtilis and Staphylococcus aureus. Also expectorant, anti-asthmatic effect. For the treatment of chronic bronchitis.

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What is Cynarin

 Cynarin (1,3-dicaffeylquinic acid). Active principle of artichoke. Therapeutic Category: Choleretic (bile stimulant). Merck Index, Twelfth Edition, Page 398, No. 276
1The body makes bile acids from cholesterol. Increasing bile acid production results in a decrease in circulating cholesterol. Improvement in digestion also results from the increased bile flow. The active ingredient in Artichoke most affecting bile production is Cynarin. Other components of Artichoke have a mild The diuretic effect.
In order to separate the several activities inherent in many herbal products, it is frequently desirable to produce dosage forms containing only the principal ingredient of interest. Thus, a finished product containing only purified Cynarin would be expected to stimulate bile secretion (and lower cholesterol) without the diuretic effect of whole artichoke extract.

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The application of the PPS R7

The PPS R7 is an integrated performance of special engineering plastics. The PPS R7 has excellent high temperature resistance, corrosion resistance, radiation-resistant, flame retardant, balanced physical and mechanical properties and excellent dimensional stability and excellent electrical properties and other characteristics, are widely used as a structural polymer materials by filling The modification is widely used as special engineering plastics. At the same time, also made a variety of functional thin films, coatings and composites, to be successful in the field of electronics, aerospace, automotive and transportation applications. In recent years, the domestic enterprises to actively research and development, and initially formed a certain production capacity, changed the situation completely dependent on imports. However, the China PPS R7 technologies also there is less product variety, high-functional products, the capacity of the urgent need to expand and other issues, these will be the focus of the next step in the development of the PPS R7.
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the information of Crocin I

In recent years, scientists have found that saffron flower contains the saffron acid (Crocin I), saffron (safranal), crocin (Crocin I) and saffron bitter element (Protocrocin) and so has a strong anti-cancer activity. Especially for blood cancer, papillary carcinoma, squamous cell tumors and soft tissue sarcoma and so has a strong inhibitory effect. The anticancer mechanism of inhibition of cancer cell DNA and RNA synthesis, inhibition of protein kinase activity and expression of the proto-oncogene, inhibit the carcinogenicity of benzo [a] pyrene and 12-O-14 acyl phosphorus ketone -13 acetate (TPA) toxicity of the substances at the molecular level to inhibit tumor formation. Semi-lethal dose of the cancer cells of 0.8 ~ 2muM toxicity is far less than retinoic acid, crocin and other anti-cancer active substances will become one of the best anti-cancer drugs of the 21st century.

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How to Buy Crocin I

Crocin I  is found in a natural carotenoid compounds, the dicarboxylic acid lipid disaccharide by gentian possession of spent acid and acetic acid formation. Its color is dark red, crystal-like, melting point is 186 ° C, when it is soluble in water, the solution is orange.Crocin principal is present in the saffron in a non-four terpenoid pigments, including crocin 1, crocin 2, crocin 3, crocin-4 and crocetin. crocin class of central blood pressure, atherosclerosis prevention and anti-thrombotic, and anti-inflammatory and treatment of soft tissue injury, liver and gallbladder, anti-tumor and other pharmacological effects.
Chemical properties
Light red-brown powder soluble in water, orange, slightly soluble in ethanol, ether and other organic solvents. α-elements present in the possession of flowers and fragrant flowers of gardenia plants, the carotenoid class of Tibetan gentian flower acid and two molecules of the binary combination of disaccharide esters. Gardenia, in addition to pigment composition, but also contains tannin, pectin, essential oils, such as mannose and chlorinated Geneen. Took possession of the yellow pigment composition of its elements, and the saffron flower in the possession of the same elements.
Melting point: 186 ℃
Use
The yellow pigment in the natural system, took possession of more stable elements, with light, heat resistance and chemical resistance of metal ions, etc., largely unaffected by pH changes color effects, especially for protein, starch, also has excellent dyeability, therefore, to noodles, cakes, candied chestnuts are mainly used in various foods. The product safe for mice to acute toxicity test, oral 15g/kg and no death cases. Add 2% of the pigment used to feed the sub-chronic toxicity test results and there is no exception, as this dose by the body (to 50kg total) conversion, equivalent per person per day intake of 200 grams. Therefore, in concentrations commonly used can be considered completely harmless. Domestic gardenia yellow pigment used in candy, cookies, egg rolls, orange juice, soft drinks, cold drinks, wine to use the test better.
Hazardous nature
WGK Germany 3F 1-8-10RTECS No. HL7380000Storage temperature 2-8 ℃
 Saffron Saffron is the prime key component of pigment. It has been shown to have anti-cancer effects, it also has antidepressant effects. According to a new study shows that crocin has aphrodisiac functions.Alias  Crocin/Saffron grain Saffron  points son type   points son quantity  C44H64O24 976.96 C A S th  94238-  chemical classification Diterpenoid two terpenoids  to source  iris secco plant Saffron Crocus sativus . the stigma of the rules case properties  > 98% light red brown powder.



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The Use of PA6 CM1017

PA6 CM1017  plastic raw materials, plastic raw materials of nylon 6 (PA6) features: Properties: Translucent, or far out milky white crystalline polymer features: thermoplastic, light weight, good toughness, chemical resistance and durability of a good editor application range of industrial production in the pan used in the manufacture of bearings, gear, cam, bevel gear, a variety of rollers, pulleys, pump impeller, the fan blades, worm gear, propeller, screw, nuts, gaskets, high pressure seals, oil gasket. oil containers, housings, hoses, cable sheathing, shearing machine pulley sets, Shaper slider, electromagnetic allocated seat, cold Chen equipment, gaskets, bearing cage, cars and tractors on a variety of pipeline, piston , ropes, belts, textile machinery and industrial equipment, zero-fog material, as well as household goods and packaging films such as polyamide resin, the English name for the polyamide, referred to as the PA. commonly known as nylon nylon, for the five major engineering plastics production the largest and most varied, the most widely used variety. Main varieties PA6, PA66, PA11,, of PA12, PA610, PA612, PA46, of PA1010 and other. PA11 and PA12 with outstanding low temperature toughness. PA46 refueling excellent heat resistance.
Nylon is widely used in machinery, automobiles, electrical appliances, textile equipment, chemical equipment, aviation, metallurgy and other fields. Its main features are: excellent mechanical properties. High mechanical strength, good toughness. Self-lubrication, abrasion. Excellent heat resistance and electrical insulation. Excellent weather resistance.
Nylon density and excellent overall performance, in order to meet the requirements of the automotive lightweight energy-efficient. Especially the use of its good mechanical strength, wear resistance, oil resistance, self-lubricating characteristics, manufacturing all kinds of bearings, gears, pulleys, oil pipelines, oil reservoir, oil gasket, protective cover, cage, wheel cover, cover, diversion board, fan, air filter housings,Radiator water chamber, brake pipe, hood, door handles.



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The Introduction of PA66 ST801

 

PA66 ST801 toughening level specification level: Injection Molding Uses: suitable for impact resistance of the products Remarks: Features: excellent impact resistance. PA properties: crystalline thermoplastic plastic, with a clear melting point, Nylon6 Tm of 220-230 ℃, Nylon66 was 260-270 ℃, Nylon with water-based and therefore their absorption, to be dried before molding, high temperature drying the nylon grain discoloration.
Properties
Translucent or opaque white crystalline polymers, with plasticity, density 1.15g/cm3. Melting point of 252 ℃. Embrittlement temperature of -30 ℃. Thermal decomposition temperature greater than 350 ℃. Continuous heat 80-120 ℃, equilibrium water absorption 2.5% to acid, alkali, aqueous solutions of most inorganic salts, alkyl halides, hydrocarbons, esters, ketones, such as corrosion, but soluble in phenol, formic acid and other polar solvents with excellent wear resistance, self-lubricating resistance, high mechanical strength, but the larger water absorption, and thus dimensional stability is poor.
Application
Widely used in the manufacture machinery, automobile, chemical, and electrical equipment parts such as gears, rollers, pulleys, rollers, pump the impeller, fan blades, high-pressure seal around, valve seats, gaskets, bushings, handles a variety of , supporting frames, wire cladding, etc. can also be made of thin films used as packaging materials. In addition, also for the production of medical equipment, sporting goods, daily necessities and so on. Modeling process
Drying: If the material is sealed before processing, then there is no need to dry. However, if the storage container is opened, it is recommended that at 85 ℃ hot air drying. If the humidity is greater than 0.2%, also need to be 105 ℃, 12 hours of vacuum drying.
Melting temperature: 260 ~ 290 ℃. Of glass additive products 275 ~ 280 ℃. Melting temperature should be avoided above 300 ℃. Mold temperature: recommended 80 ℃. Mold temperature will affect the degree of crystallinity, and degree of crystallinity will affect the physical properties for thin-walled plastic parts, if the die temperature below 40 ℃, the plastic parts of the crystallinity will change over time, in order to maintain the geometric stability of the plastic parts, the need for annealing.
Injection pressure: usually 750 ~ 1250bar, depending on material and product design.
Injection speed: high speed (for enhanced material should be slightly lower).
Runners and gates: As of PA66 coagulation time is very short, so the gate is important. Gate aperture not less than 0.5 * t (where t is the thickness of plastic parts). If you use the hot runner, gate size should be less than smaller using conventional flow channel, as hot runner can help prevent premature solidification of materials. If sneak into the gate, the gate should be the minimum diameter of 0.75mm.
Chemical Physics
PA66 polyamide material has a higher melting point and it is a semi-crystalline - crystalline materials. PA66 at high temperature to maintain a strong strength and stiffness. PA66 still has moisture in the molding, which mainly depends on the degree on material composition, thickness, and environmental conditions in the product design, we must consider the impact of moisture on the stability of the geometric order to improve the mechanical properties of PA66, often adding a variety of modifiers. Glass is the most common additives, and sometimes also added to improve impact resistance synthetic rubber, such as EPDM and SBR, etc.. PA66 low viscosity, so the flow is very good (but not as good as PA6). The nature of the components can be used to process thin and it's Viscosity is very sensitive to temperature change. PA66 shrinkage of 1% to 2%, and glass fiber additives can reduce the shrinkage to 0.2% to 1% shrinkage in the flow direction and perpendicular to the direction and flow direction The differences are larger. PA66 with alcohol-resistant to many solvents, but the acid chloride and other agents of the resistance is weak.

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The Introduction of PP 1126NK

性    能	1126NK	单位	条件	测试法ASTM
熔融指数	11	g/10min	230℃2.16kg	D1238
屈服抗张强度	34	N/mm	-	D638
CHARPY 缺口冲击强度	2.8	MJ/mm	23℃	DIN 53453
SHEAR 模量	700	N/mm	-	DIN 53457
球压痕硬度	85	N/mm	-	DIN 53456
热变形温度	110	℃	0.45N/mm	D648
应     用	食品包装,果蔬包装薄膜,层合薄膜

Product name：PP 1126NK 
Features:

1.  Physical properties: Polypropylene is non-toxic, odorless, tasteless white high crystallinity of the polymer, the density is only 0.90-0.91g / m, is the lightest of all varieties of plastic.
2. Mechanical properties: resistance to bending fatigue.
3. Tthermal performance: PP has good heat resistance, melting point at 164-170 ℃, 100 ℃ for products in the temperature sterilization, without external forces, 150 ℃ is not deformed. Embrittlement temperature of -35 ℃, below -35 ℃ embrittlement occurs, cold resistance than polyethylene;
4. Electrical properties: high frequency polypropylene insulation performance, because it is almost non-absorbent, so the insulation from humidity and it has a higher dielectric constant and temperature increases, heat can be used to make electrical insulation products, it is also very high breakdown voltage, suitable for electrical accessories, anti-voltage, arc resistance is good, but the static and high copper contacts is easy with aging;
5. Weather resistance: very sensitive to UV polypropylene, adding zinc oxide, thio Dilauroyl acid ester, carbon black or similar white fillers can improve its anti-aging properties.

Uses: food packaging, fruit and vegetable packaging film, laminated film



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