About Vardenafil

Vardenafil belongs to a group of medicines that delay the action of enzymes called phosphodiesterases that can interfere with erectile function. Vardenafil is used to treat men with erectile dysfunction (also called sexual impotence) because it helps to maintain an erection that is produced when the penis is stroked. Vardenafil (INN) is a PDE5 inhibitor used for treating erectile dysfunction .Vardenafil's indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both sildenafil and vardenafil. Vardenafil's relatively short effective time is comparable to but somewhat longer than sildenafil's.
Beyond its indications for erectile dysfunction, Vardenafil  may be effective in the treatment of premature ejaculation, where it may significantly increase the time from vaginal penetration to ejaculation.