Combretastatin Information

Combretastatin is a small organic molecule found in the bark of the African bush willow tree Combretum caffrum (photo, right), identified 21 years ago by Professor George R. Pettit, the Director of the Cancer Research Institute based at Arizona State University in the USA. (See Pettit et al. Can. J. Chem. 610 (1982), 1374). Scientists at the CRI have not only completed a total synthesis for combretastatin, but have isolated it on scales large enough to allow clinical testing, and they have also produced water-soluble phosphate derivatives, which are helping the drug's delivery to patients. Professor Pettit, like many great scientists, is driven towards a goal, that of finding treatments for cancers. He has many lead compounds and is a well-known scientist in the world of Natural Products Chemistry. I had the pleasure of working with the legendary "medicine man" from 1992-1994.
The beautiful Bush Willow tree only grows on the banks of rivers in the Eastern Cape Province of South Africa. Local historians believe that for over 2000 years Arabians traded for the bark with the San people (Bushmen). The bark was probably used as a general tonic in those days, because, apart from its anti-cancer properties, the bark also produces a feeling of improved general well being. Like many useful natural extracts it can be harmful in the wrong dose. This can be clearly illustrated by the fact that it has been used as a poison for Zulu spears. It is now possible to order the bark online at a cost of $22/100g Only take medicines, of any kind, in consultation with a trained, accredited medical practitioner.
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What is Corilagin

Corilagin is a gallotannin. It can be found in Alchornea glandulosa.

References

1,New TNF- Releasing Inhibitors, Geraniin and Corilagin, in Leaves of Acer nikoense, Megusurino-ki

  Biological & Pharmaceutical Bulletin  Vol. 24 (2001) , No. 10 1145

2,Antiatherogenic Effects of Phyllanthus Emblica Associated with Corilagin and its Analogue

   YAKUGAKU ZASSHI Vol. 125 (2005) , No. 7 587-591

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Description of Fungal Amylase

Product name  : Fungal Amylase
Applications : Baking industry,Increasing yield of beer and alcohol breweries by supplement with malts,Feed additives,High maltose syrup (D.E. 40 to 45) manufacturing.
Description : Deerland Fungal Amylase Concentrate is an enzyme preparation derived from Aspergillus oryzae and contains high alpha-Amylase activity that converts solubilized or liquefied starch to mainly maltose.
Request Info : 
Supplier : Deerland Enzymes
Contact info  : 3800 Cobb International Blvd. Kennesaw. GA 30152, United States
Phone:800-697-8179 
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The role of the aconitine

Aconitine Aconitum, Aconitum, monkshood plant, the main toxic components. Oral pure aconitine 0.2mg can be poisoned, 3-5mg can be lethal. The common folk Aconitum, Aconitum plants to cook the wine. This product has analgesic effects, clinically used to relieve pain, especially for digestive system cancer pain; topical when the paralysis of the peripheral nerve endings, produce a local anesthetic and analgesic effects; anti-inflammatory effect, This product is highly toxic, can excited paralysis of sensory nerves and central nervous, excited, paralysis of cholinergic nerves and respiratory center, excited cardiac vagal directly toxic to myocardial cells. There are sweating.
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The nature of the catechin (C)

Catechin (C) is a white to brown crystalline powder, discoloration in the air. Density 1.54g/cm3. The melting point of about 200 ° C (decomposition). Dissolved in 50 parts of water; soluble in alcohol, ether. Leaves, Ilex plant holly (Ilex chi-nensis Sims) of leaves and other plants exist in the scales beginning of fern plants black fern Stenoloma chusanum (L.) Ching]. Catechin (C) has an antibacterial effect in vitro tests have varying degrees of inhibitory effect of Pseudomonas aeruginosa, Escherichia coli, Salmonella typhi, Shigella, Alcaligenes and Bacillus subtilis and Staphylococcus aureus. Also expectorant, anti-asthmatic effect. For the treatment of chronic bronchitis.

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What is Cynarin

 Cynarin (1,3-dicaffeylquinic acid). Active principle of artichoke. Therapeutic Category: Choleretic (bile stimulant). Merck Index, Twelfth Edition, Page 398, No. 276
1The body makes bile acids from cholesterol. Increasing bile acid production results in a decrease in circulating cholesterol. Improvement in digestion also results from the increased bile flow. The active ingredient in Artichoke most affecting bile production is Cynarin. Other components of Artichoke have a mild The diuretic effect.
In order to separate the several activities inherent in many herbal products, it is frequently desirable to produce dosage forms containing only the principal ingredient of interest. Thus, a finished product containing only purified Cynarin would be expected to stimulate bile secretion (and lower cholesterol) without the diuretic effect of whole artichoke extract.

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The application of the PPS R7

The PPS R7 is an integrated performance of special engineering plastics. The PPS R7 has excellent high temperature resistance, corrosion resistance, radiation-resistant, flame retardant, balanced physical and mechanical properties and excellent dimensional stability and excellent electrical properties and other characteristics, are widely used as a structural polymer materials by filling The modification is widely used as special engineering plastics. At the same time, also made a variety of functional thin films, coatings and composites, to be successful in the field of electronics, aerospace, automotive and transportation applications. In recent years, the domestic enterprises to actively research and development, and initially formed a certain production capacity, changed the situation completely dependent on imports. However, the China PPS R7 technologies also there is less product variety, high-functional products, the capacity of the urgent need to expand and other issues, these will be the focus of the next step in the development of the PPS R7.
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